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Search Results for " hif-1α/2α inhibitor "

8

Compounds

Cat No. Product Name Synonyms Targets
T36711 FM19G11 FM19G11,HIF-1alpha/2alpha Inhibitor HIF
FM19G11 is an inhibitor of hypoxia inducible factor (HIF) α-subunit (IC50 = 80 nM in hypoxia induced luciferase assay).
T0692 Allopurinol Zyloric,Zyloprim,Lopurin ROS , Xanthine Oxidase
Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.
T6376 Allopurinol Sodium Allopurinol sodium salt,Sodium allopurinol ROS
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
T17009 TC-S 7009 HIF
TC-S 7009 is a potent and selective HIF- inhibitor (Kd: 81 nM). The affinity of TC-S 7009 to HIF- was higher than that of HIF- (Kd >> 5μM). TC-S 7009 disrupts HIF- heterodimerization, reduces HIF- target gene e...
T6804 Chetomin Chaetomin,NSC289491,BRN0077366 Apoptosis , HSP , HIF
Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF- and HIF- to p300 at low nanomolar concentrations.
T61442 HIF-1/-IN-1
HIF-1/-IN-1, an orally active compound, functions as an inhibitor of HIF-. Its inhibitory effect on HIF- activity is significant, with an IC 50 value of 0.92 μM. Furthermore, HIF-1/-IN-1 has the ability to decrea...
TP2046 TAT-cyclo-CLLFVY
Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-, but not HIF-, with HIF-1β (IC50 = 1.3 μM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expressi...
T69966 Roxadustat-d5
Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1....
TargetMol